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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-125b
ncRNA name hsa-miR-125b
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, normal retina samples
Methods microarray
Expression pattern down-regulated
Functional description As a result, a set of 24 DE-miRs were selected, including nine upregulated and 15 downregulated miRNAs between the RB and healthy retina samples. Hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A.
PubMed ID 26730174
Year 2015
Title miRNA signature identification of retinoblastoma and the correlations between differentially expressed miRNAs during retinoblastoma progression.
Drug-related ncRNA NO

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